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Abstract #2096

Whole-Tumor Quantitative Apparent Diffusion Coefficient Histogram Analysis in Differentiating intrahepatic mass-forming cholangiocarcinoma from poorly differentiated hepatocellular carcinoma

Xianlun Zou1, Yaqi Shen1, Yao Hu1, Zhen Li1, and Daoyu Hu1

1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wu han, People's Republic of China

Differentiating intrahepatic mass-forming cholangiocarcinoma (IMCC) and poorly differentiated hepatocellular carcinoma(pHCC) is often difficult for radiologists, but it is important for providing appropriate treatments. In our study, we use noncontrast MRI with diffusion-weighted imaging in combination with whole-tumor quantitative apparent diffusion coefficient (ADC) histogram analysis to differentiate IMCC from pHCC. The result reveals that ADC histogram analysis based on the whole-tumor can be considered a useful and noninvasive method to help differentiate IMCC from pHCC. Especially ADC25% of histogram analysis allows differentiation of IMCC from pHCC with higher accuracy.

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