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Abstract #2100

Dynamic contrast-enhanced MRI for uterine cervical cancer: correlations with clinical staging and pathologic types

Xiaoduo Yu1, Meng Lin1, Lizhi Xie2, Han Ouyang1, and Chunwu Zhou1

1Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China, 2GE Healthcare, MR Research China, Beijing

Tumor blood supply is closely related to the tumor occurrence, development, metastasis and prognosis. MRI is the optimal imaging method for investigating uterine cervical carcinoma, which provides excellent morphological information using conventional series. Additionally, the tumor perfusion information can be quantitatively assessed by dynamic contrast-enhanced MRI (DCE-MRI). DCE derived parameters include MaxSlop, CER, IAUGC, Ktrans, Kep and Ve. Our results showed mild negative correlation to clinical FIGO stage based on mean and maximum of Ktrans and Kep, increased minimum MaxSlop, and increased max- and mini-mum Ktrans in squamous cell carcinoma than those of adenocarcinoma. DCE-MRI is a significant supplement to provide valuable morphological information that contributes to clinical decision-making and prognosis prediction.

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