Abstract #2107

10 Second Temporal Resolution of Early Enhancement Visualization: Framework for Fast Breast MRI Screening

Jorge E Jimenez¹, Roberta M Strigel^1,2,3, Kevin M Johnson¹, Leah C Henze Bancroft¹, Scott B Reeder^1,2,4,5,6, and Walter F Block^1,2,4

¹Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ²Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, ³Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, United States, ⁴Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁵Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States, ⁶Department of Emergency Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States

In this work, we present a new methodology for an abbreviated dynamic contrast enhanced (DCE) MRI breast screening protocol. The methodology relays on a novel dynamic reconstruction scheme, local low-rank, applied to breast MR imaging for the first time. Our work provides the framework for a high resolution (0.83 mm isotropic), ultra-fast (10 second volumetric frame rate) imaging technology to deliver detailed information of the early enhancement phase of breast lesions, preserving diagnostic accuracy while shortening exam times. We demonstrate the feasibility of the proposed approach.

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