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Abstract #2135

Is ADC heterogeneity helpful in characterizing ductal carcinoma in situ (DCIS) at 3.0T breast MRI

Oi Lei Wong1, Gladys Goh Lo2, Jing Yuan1, Helen Hei Lun Chan2, Ting Ting Wong3, and Polly Suk Yee Cheung3

1Medical Physics and Research Department, Hong Kong Sanatorium & Hosptial, Hong Kong, Hong Kong, 2Department of Diagnostic & Interventional Radiology, Hong Kong Sanatorium & Hosptial, Hong Kong, Hong Kong, 3Breast Care Center, Hong Kong Sanatorium & Hosptial, Hong Kong, Hong Kong

In this study, we intended to investigate the relationship between ADC heterogeneity of DCIS lesions and DCIS lesioxn morphology, histological grade and BIRADS classification using 3T DW breast MRI. Increasing heterogeneity was observed with increasing DCIS histological grade and increasing BIRADS, but not reaching significance level, was observed based on our results. This study was mainly limited in the small numbers of DCIS lesions, so statistical power has to be further strengthened in future studies with larger sample size.

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