Meeting Banner
Abstract #2161

Determination of RF and acquisition properties for optimal scan performance in 19F-MRI of inhaled perfluoropropane

Mary Neal1, Prosenjit Dutta1, John Simpson2, Andrew Blamire1, and Pete Thelwall1

1Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom, 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

19F-MRI of inhaled perfluoropropane gas allows assessment of lung ventilation properties with a thermally polarised tracer gas. Due to the scarcity of signal from the non-hyperpolarised gas-phase imaging agent, optimal scan protocol design plays a critical role in image quality. Acquisition variables and coil power performance were modelled to determine the optimal image acquisition parameters for a spoiled gradient echo pulse sequence for human 19F birdcage and chest surface coils. Application of optimised scan protocols to human studies shows acceptable image quality for assessment of lung function.

This abstract and the presentation materials are available to members only; a login is required.

Join Here