Abstract #2251

Characteristics of Cortical and Subcortical Abnormalities in Pediatric Attention Deficit Hyperactivity Disorder patients

Lu Lu¹, Lianqing Zhang¹, Xuan Bu¹, Hailong Li¹, Xiaoxiao Hu¹, Ying Chen¹, Xinyu Hu¹, Lanting Guo², Qiyong Gong ¹, and Xiaoqi Huang¹

¹Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, People's Republic of China, ²Department of Psychiatry, West China Hospital of Sichuan University

The current study combine the analysis of the cortical measures and subcortical structures’ volume to evaluate the cerebral structure alterations in a relative large drug-naive ADHD sample. In addition, we also invest the anatomical–age correlation between two groups. Our findings (i) highlighted the crucial role of the frontostriatal circuits in the pathophysiology of ADHD, (ii) indicated the abnormality in neural development trajectory in ADHD.

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