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Abstract #2251

Characteristics of Cortical and Subcortical Abnormalities in Pediatric Attention Deficit Hyperactivity Disorder patients

Lu Lu1, Lianqing Zhang1, Xuan Bu1, Hailong Li1, Xiaoxiao Hu1, Ying Chen1, Xinyu Hu1, Lanting Guo2, Qiyong Gong 1, and Xiaoqi Huang1

1Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, People's Republic of China, 2Department of Psychiatry, West China Hospital of Sichuan University

The current study combine the analysis of the cortical measures and subcortical structures’ volume to evaluate the cerebral structure alterations in a relative large drug-naive ADHD sample. In addition, we also invest the anatomical–age correlation between two groups. Our findings (i) highlighted the crucial role of the frontostriatal circuits in the pathophysiology of ADHD, (ii) indicated the abnormality in neural development trajectory in ADHD.

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