Abstract #2290

Structural thalamocortical connectivity in the developing infant brain

Rali Dimitrova^1,2, Jonathan O'Muircheartaigh^1,2, Judit Ciarrusta^1,2, Dafnis Batalle¹, Emer Hughes¹, Johannes Steinweg¹, Emily Perry², Johanna Kangas², Ines Pote², Serena Counsell¹, Jo Hajnal¹, Declan Murphy², David Edwards¹, and Grainne McAlonan²

¹Centre for the Developing Brain, King's College London, London, United Kingdom, ²Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom

Thalamocortical development in early life is crucial for normal brain functioning and abnormalities to these networks are thought to underpin atypical neurodevelopment. However, to date examination of this system in the infant has been hampered by the lack of age-appropriate population atlases. In this study we circumvent this problem by applying independent component analysis to parcellate the thalamocortical projections and their underlying thalamic seed in 6-months-old infants using diffusion MRI.

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