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Abstract #2294

Comparison of postnatal trajectory of neonatal white matter development between preterm and term neonates during the neonatal stage

Chao Jin1, Yanyan Li1, Xianjun Li1,2, Miaomiao Wang1, Congcong Liu1, Jie Gao1, Qinli Sun1, Xiaocheng Wei3, and Jian Yang1,2

1Department of Diagnostic Radiology, the first Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China, 2Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, People's Republic of China, 3MR Research China, GE Healthcare, Beijing, People's Republic of China

Due to exposure to extrauterine environment, neonatal brain development is in totally different ways after birth, compared with the ‘protected’ gestation. However, little is known about the postnatal trajectory of neonatal brain development, especially for the differences between preterm and term neonates. This study aims to investigate the postnatal maturation of brain white matter (WM) during the neonatal stage and further provide comparison between preterm and term neonates. Our results suggest that during the neonatal stage, preterm neonates show weaker development capacity than term in optical and somatosensory functions, while present catching up maturation in motor function.

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