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Abstract #2307

Correlation Between Cerebral Blood Flow And Whole Brain Perfusion In Children Undergoing Deep Sedation.

Malek I MAKKI1,2, Ruth O'Gorman3, Olivier Baledent2, Philip Buhler4, Markus Weiss4, Christian Kellenberger5, Ianina Scheer5, and Achim Schmitz4

1MRI Research, University Children Hospital, Zurcih, Switzerland, 2BioFlow, University Picardie Jules Verne, Amiens, France, 3MRI Research, University Children Hospital, Zurich, Switzerland, 4Anesthesia, University Children Hospital, Zurich, Switzerland, 5Radiology, University Children Hospital, Zurich, Switzerland

Anaesthetics such as those used for sedation in paediatric MRI affect cerebral blood flow and hemodynamics to varying degrees. This study examines the link between brain perfusion measured by arterial-spin-labelling and cerebral blood flow measured by phase-contrast MRI in 2 cohorts of children undergoing sedation either with propofol or a combination of propofol and ketamine. Significant correlations were observed between these 2 variables for both groups.

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