Abstract #2307

Correlation Between Cerebral Blood Flow And Whole Brain Perfusion In Children Undergoing Deep Sedation.

Malek I MAKKI^1,2, Ruth O'Gorman³, Olivier Baledent², Philip Buhler⁴, Markus Weiss⁴, Christian Kellenberger⁵, Ianina Scheer⁵, and Achim Schmitz⁴

¹MRI Research, University Children Hospital, Zurcih, Switzerland, ²BioFlow, University Picardie Jules Verne, Amiens, France, ³MRI Research, University Children Hospital, Zurich, Switzerland, ⁴Anesthesia, University Children Hospital, Zurich, Switzerland, ⁵Radiology, University Children Hospital, Zurich, Switzerland

Anaesthetics such as those used for sedation in paediatric MRI affect cerebral blood flow and hemodynamics to varying degrees. This study examines the link between brain perfusion measured by arterial-spin-labelling and cerebral blood flow measured by phase-contrast MRI in 2 cohorts of children undergoing sedation either with propofol or a combination of propofol and ketamine. Significant correlations were observed between these 2 variables for both groups.

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