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Abstract #2354

Acupoint-Specific Effect of Acupuncture in Alzheimer’s Disease: A Functional MRI Study

Yi Shan1, Yunpeng Bian2, Zhiqun Wang3, Zhilian Zhao1, Mo Zhang1, Jie Lu1, and Kuncheng Li1

1Xuanwu hospital, Capital Medical University, Beijing, People's Republic of China, 2University of Science and Technology of China, Hefei, China, 3Oriental Hospital,Beijing University of Chinese Medicine, Beijing, China

Acupuncture has been a major therapeutic method in Chinese medicine for treating Alzheimer’s disease (AD) with validation and safety. In this study, we use functional magnetic resonance imaging (fMRI) to investigate the acupoint-specific effect of acupuncture in treating for AD. We found acupuncture at real acupoints activated brain areas primarily in the left uvula, right superior temporal gyrus and right uncus, while acupuncture at sham acupoints only activated areas in the left insula. These results showed that acupoint-specific effect of acupuncture presented by fMRI may help to facilitate its clinical use in AD treatment.

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