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Abstract #2417

Magnetic flux density comparisons between in-vivo TACS human Magnetic Resonance Electrical Impedance Tomography measurements and MRI-derived human computational models

Aprinda Indahlastari1, Aditya Kumar Kasinadhuni2, Kevin Castellano2, Christopher Saar1, Casey Weigel1, Bakir Mousa1, Munish Chauhan1, Thomas H Mareci2, and Rosalind J Sadleir1

1Arizona State University, Tempe, AZ, United States, 2University of Florida

actual current densities applied to the brain in neuromodulation therapies. MREIT can be used to determine actual current densities delivered to the brain by measuring Bz. Here we present Bz distributions resulting from trans-temporal current injection obtained from MREIT imaging during 10 Hz TACS in a healthy human subject. Comparisons of MREIT results to MRI-derived computational models suggested that actual contact areas between electrodes and scalp may be smaller than electrode surface areas, and in-vivo tissue conductivity values, particularly skin and skull, may be different than assumed.

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