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Abstract #2469

Diffusion discriminant for mild cognitive impairment in Parkinson’s disease

Aziz M. Ulug1,2, Esin Ozturk-Isik1, Ani Kicik3,4, Emel Erdogdu5, Sevim Cengiz1, Dilek Betul Arslan1, Seda Buker6, Ali Bayram3,4, Cigdem Ulasoglu-Yildiz3,4, Elif Kurt3,4, Zeynep Tufekcioglu6, Basar Bilgic6, Hasmet A. Hanagasi6, Tamer Demiralp3,7, and Hakan Gurvit6

1Institute of Biomedical Engineering, Bogazici University, Istanbul, Turkey, 2CorTechs Labs, San Diego, CA, United States, 3Hulusi Behcet Life Sciences Research Center, Istanbul University, Istanbul, Turkey, 4Department of Neuroscience, Istanbul University, Istanbul, Turkey, 5Institute of Psychology and Cognition Research, University of Bremen, Bremen, Germany, 6Department of Neurology, Istanbul University, Istanbul, Turkey, 7Department of Physiology, Istanbul University, Istanbul, Turkey

High percentage of Parkinson’s disease patients develop cognitive impairment during the course of the disease progression. An imaging marker that can identify the patients who will develop cognitive impairment would be helpful in deciding the treatment strategy for these patients. We have used diffusion tensor imaging to identify brain structures which can be utilized to discriminate between Parkinson’s patients with mild cognitive impairment and without cognitive deficits.

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