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Abstract #2533

Sensitivity to pathological normal appearing white matter damage in multiples sclerosis – a comparison of DTI and DKI

Tim Sprenger1,2, Michael Czisch3, Brice Fernandez4, Ines Eidner3, Jonathan I. Sperl5, Axel Haase1, Frank Weber3, Marion I. Menzel5, and Philipp G. Sämann3

1Technische Universität München, Munich, Germany, 2GE Global Research, Munich, Germany, 3Max Planck Institute of Psychiatry, Munich, Germany, 4GE Heathcare, Paris, France, 5GE Global Research, Munich

A systematic comparison of diffusion tensor imaging (DTI) and diffusional kurtosis imaging (DKI) regarding the sensitivity to non-pathological white matter in multiple sclerosis is presented. We found first indications for a higher sensitivity of DKI compared with DTI in the normal appearing white matter compartment.

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