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Abstract #2540

Optimization of Neurite Orientation Density and Dispersion Imaging (NODDI) for In Situ Imaging

Ken Sakaie1, Mark Lowe1, and Daniel Ontaneda2

1Imaging Institute, The Cleveland Clinic, Cleveland, OH, United States, 2Mellen Center for Multiple Sclerosis, The Cleveland Clinic, Cleveland, OH, United States

In situ imaging is a valuable context for validation of imaging measures against histology. This contribution describes optimization of diffusion MRI for NODDI in in situ imaging of a multiple sclerosis patient. The results are expected to facilitate validation of advanced diffusion MRI and other tissue microstructure meausrements.

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