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Abstract #2593

Accumulated Thermal Dose in MR-Guided Focused Ultrasound for the Treatment of Essential Tremor

Yuexi Huang1, Nir Lipsman2, Michael L. Schwartz2, Vibhor Krishna3, Francesco Sammartino3, Andres Lozano3, and Kullervo Hynynen1,4

1Sunnybrook Research Institute, Toronto, ON, Canada, 2Division of Neurosurgery, Sunnybrook Health Sciences Centre, Toronto, ON, Canada, 3Division of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada, 4Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada

In focused ultrasound treatment of essential tremor, MR temperature and thermal dose measurements were crucial in guiding acoustic parameters. In this study, accumulated thermal doses from repeated sonications were integrated after chemical-shift artifacts were corrected retrospectively. Accumulated thermal dose measurements showed good correlation to lesion size in followup MR imaging.

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