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Abstract #2606

Clinical Outcome of Globus pallidus internus or subthalamic nucleus deep brain stimulation for Parkinson's disease using MRI-guided localization and verify with microelectrode

Sherman SM Lo1, WL Poon1, KW Tang1, and TL Poon2

1Department of Radiology & Imaging, Queen Elizabeth Hospital, Kowloon, Hong Kong, 2Department of Neurosurgery, Queen Elizabeth Hospital, Kowloon, Hong Kong

Globus pallidus internus (GPi) and Subthalamic nucleus (STN) are the two main target for deep brain stimulation (DBS) in treatment for patients with advanced Parkinson's disease (PD) not respond to medical therapies. MRI brain imaging is used for selection of patients for DBS and localize the target nucleus. This study confirms that GPi/STN-DBS may be placed with high accuracy by using a correct and optimal MRI-guided sequences. Correct deep brain stimulation electodes placement can provides a safe and effective treatment for severe Parkinson’s disease not responsive to medical therapies.

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