Abstract #2615

2D UTE-based MR thermometry of frozen tissue: feasibility during in vivo MRI-guided cryoablation

Christiaan G. Overduin¹, Axel J. Krafft², Michael Bock², Hans JF Langenhuijsen³, Sjoerd F.M. Jenniskens¹, Jurgen J. Fütterer^1,4, and Tom W.J. Scheenen¹

¹Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, Netherlands, ²Radiology - Medical Physics, Medical Center University of Freiburg, Freiburg, Germany, ³Urology, Radboud University Medical Centre, Nijmegen, Netherlands, ⁴MIRA Institute for Biomedical Engineering and Technical Medicine, University of Twente, Enschede, Netherlands

This study assessed the feasibility of 2D UTE-based MR thermometry of frozen tissue during in vivo MRI-guided cryoablation. Axial 2D UTE images were acquired at the end of the first and second freeze cycle during an MRI-guided renal cryoablation procedure. Measurable MR signal could be obtained from frozen tissue. MR temperature maps were estimated using a relative signal level calibration performed in ex-vivo porcine muscle. Our work demonstrates the feasibility of 2D UTE-based MR thermometry of frozen tissue during in vivo MRI-guided cryoablation, which could be an important step towards clinical application of this technique.

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