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Abstract #2722

Multi-parametric cardiac MRI for T1 mapping and cine imaging using iterative model-based image reconstruction

Kirsten Miriam Becker1, Jeanette Schulz-Menger2,3, Tobias Schaeffter1,4, and Christoph Kolbitsch 1,4

1Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, 2Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center (ECRC), Berlin, Germany, 3Department of Cardiology and Nephrology, HELIOS Klinikum Berlin Buch, Berlin, Germany, 4Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom

In cardiac MRI, different diagnostic parameters are obtained in separate scans, leading to long examination times. In this work, we present an iterative model-based reconstruction approach for continuously acquired data, which provides native T1 maps and functional cine images within a single breath hold. The continuous acquisition allows for T1 reconstruction for different cardiac phases. Evaluation in a phantom demonstrated accurate T1 values (R²>0.99) and insensitivity to heart rates, with T1 variations of less than 5% (50 to 90 bpm). In three healthy volunteers T1 maps were assessed for diastole and systole and cine images had a consistent dark-blood contrast.

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