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Abstract #2744

An in-vivo comparison of STEAM and 2nd order motion compensated spin-echo imaging in multi-phase cardiac DTI at 3T

Andrew David Scott1,2, Sonia Nielles-Vallespin1,3, Pedro Ferreira1,2, Zohya Khalique1, Dudley Pennell1,2, and David Firmin1,2

1Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, United Kingdom, 2National Heart and Lung Institute, Imperial College London, London, United Kingdom, 3National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, United States

Cardiac diffusion tensor imaging (cDTI) is a novel non-invasive method of interrogating myocardial microstructure that has seen a recent surge in interest. Many of the most interesting clinical results were obtained using stimulated echo acquisition mode (STEAM) imaging at multiple cardiac phases. Recently however, spin-echo cDTI with second order motion compensated diffusion gradients (M012-SE) was proposed. In this study we report results of a comparison of M012-SE and STEAM imaging in multiple cardiac phases at 3T in 15 healthy subjects with matched sequence parameters. While M012-SE provides comparable quality data in systole, STEAM is the more reliable technique in diastole.

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