A Look-Locker scout is used for optimal inversion time (TI) determination of myocardial nulling in Late Gadolinium Enhancement (LGE) Cardiac Magnetic Resonance. Recently, novel LGE technique variants such as the Wideband approach have been proposed, and these approaches can lead to variability in the signal evolution between the Look-Locker TI-scout and LGE. In this study, we propose a Modified Look-Locker Inversion (MOLLI)-based TI-scout that closely matches its signal evolution to that of any LGE variant. Bloch simulation and phantom evaluation are performed to compare the null-times from the conventional LL-based and proposed MOLLI-based approaches against the LGE protocol over a range of clinically relevant T1 values observed in viability imaging.
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