The purpose of this study is to compare the MRA image contrast of SNAP and TOF sequences in in-vivo cerebral artery images and explore the explanation of the observation by theoretical simulation. We found TOF MRA showed better artery-background contrast than SNAP MRA in proximal large cerebral artery for all cases, but worse in distal small cerebral artery for most of the cases. The theoretical simulation considering the blood velocity and the blood travel distance in imaging slab further validated this observation, suggesting the contrast difference between SNAP and TOF were related to blood velocity and travel distance.
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