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Abstract #2802

Novel ASL-based flow imaging for cardiovascular hemodynamics and valvular function visualization: comparison with a feasibility study

Yasuhiro Goto1, Michinobu Nagao2, Kenji Fukushima2, Masami Yoneyama3, Hitoshi Tadenuma1, Mamoru Takeyama1, and Shuji Sakai2

1Department of Radiological services, Tokyo Women’s Medical University Hospital, Tokyo, Japan, 2Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women’s Medical University Hospital, Tokyo, Japan, 3Philips Electronics Japan, Tokyo, Japan

We developed a novel ASL-based flow imaging (ASL-Flow) with modified flow-sensitive alternating inversion recovery technique and Look-Locker sequence to evaluate cardiovascular hemodynamics and valvular dysfunction. We validate that time-intensity curves of pulmonary artery form ASL-Flow matches for time-velocity curves from 2D phase-contrast MRI. ASL-Flow can visualize more clearly regurgitateion and stenotic jet in valvular diseases than standard cine imaging. The scan time for ASL-Flow is short (15 seconds/slice), and the image reconstruction needs no special software; therefore, this is easy to clinically use. We promise that ASL-Flow is a feasible non-contrast imaging to detect hemodynamics abnormality in structural heart disease.

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