Accurate diagnosis of acute deep vein thrombosis (DVT) is relevant for appropriate treatment and avoiding life-threatening events. Recently proposed MR black-blood thrombus imaging (BTI) has demonstrated the potential to provide high sensitive and specific diagnosis of DVT. However, previous studies were performed at 3T and patients investigated were all in subacute to chronic phases. It remains unclear that if BTI could be used for the diagnosis of acute DVT and could work at 1.5T. Therefore, we sought to prospectively assess whether BTI is feasible at 1.5T for diagnosis of acute DVT, using contrast-enhanced MR venography as the standard reference.