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Abstract #2824

Voxel-by-Voxel 4D Flow Based Assessment of Retrograde Flow in the Aorta

Xin Shen1, Kenichiro Suwa2, Alex J Barker2, Susanne Schnell2, Jeremy D Collins2, James C Carr2, and Michael Markl1,2

1Biomedical Engineering, Northwestern University, Chicago, IL, United States, 2Radiology, Northwestern University, Chicago, IL, United States

Retrograde fraction stratifies the degree of aortic regurgitation (AR) in patients with aortic valve disease. The purpose of this study was to develop 4D flow based voxel-by-voxel regional analysis of forward flow, reverse flow, and retrograde fraction with full volumetric coverage of the aorta. In a study with 10 subjects (5 healthy controls, 5 patients with AR), reverse flow and retrograde fraction maps were used to systematically analyze regional flow patterns and assess differences between standard (plane-wise) and voxel-by-voxel quantification of AR.

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