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Abstract #2852

4D flow MR measurements for functional assessment of idiopathic pulmonary arterial hypertension: comparison between patients and healthy volunteers

Xiaole Wang1, Yunlong Yue2, Lei Pan3, Hong Jiang3, Yunduo Li1, and Rui Li1

1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People's Republic of China, 2Department of MR, Beijing Shijitan Hospital of Capital Medical University, 3Department of Pulmonary Vascular Disease and Geriatric Medicine, Beijing Shijitan Hospital of Capital Medical University

We applied parameter analysis in 4D flow imaging for pulmonary artery hypertension (PAH) and compare the MR parameters between five patients with iPAH and five healthy volunteers. Compared with healthy volunteers, patients with idiopathic PAH have more retrograde flow in MPA, enlarger area of MPA, higher peak acceleration. And Plane-to-plane variations of these parameters were evaluated using the Bland-Altman comparisons, some parameters have relatively low variations which means they can be calculated through 2D flow imaging. In conclusion, MRI results show that the effect of increased pulmonary artery pressure and resistance has influence the flow in MPA.

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