Chronic Obstructive Pulmonary Disease is the third leading cause of death in the United States, and affects 24 million Americans with over 65 million people affected world-wide. Up-to 58% of patients develop exertional pulmonary hypertension and right ventricular volume changes. Understanding this phenomenon, known as cor pulmonale can help us gain insight into the complex pathophysiology involved. This pilot study attempts to apply 4D flow MRI in patients with varying degrees of COPD, and assess the feasibility, reproducibility and accuracy of this technique.
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