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Abstract #2877

Respiratory variation in left ventricular cardiac function with 3D double-golden-angle whole-heart cine imaging

Karen Holst1, Martin Ugander1, and Andreas Sigfridsson1

1Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden

Respiratory variation in ventricular volume can potentially provide clinically important information in cardiac diseases involving left ventricular stiffness changes, and can be measured using respiratory resolved imaging. 3D double-golden-angle radial data were acquired during free breathing, and respiratory self-gating signals were extracted from k-space. All radial spokes were sorted into 8 respiratory phases and one end-diastolic cardiac phase and left ventricular end-diastolic volume (EDV) was segmented from a short-axis image stack. Respiratory induced changes in EDV were demonstrated and changed 9.0±2.3 % with respect to maximum expiratory EDV.

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