The purpose of this study was to assess the feasibility of using GRASP DCE-MRI for contrast kinetic analysis to determine lesion malignancy. This IRB-approved retrospective study included 73 women who underwent MRI-guided biopsy scans. The plasma flow in the malignant group was significantly higher than that of the benign group with the area under the curve of 0.77. The results in this study successfully demonstrate that the GRASP DCE-MRI method can be used to acquire adequate high-temporal and high-spatial resolution images of the breast for contrast kinetic analysis.
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