Radiation-induced brain perfusion changes after radiotherapy have not been studied extensively with DSC-MRI. Tumour perfusion is often normalised to contralateral normal-appearing white matter, why knowledge about radiation effects on perfusion in normal brain tissue is essential. Ten patients were examined with DSC-MRI at 1.5 T before and repeatedly after RT. Multiple volumes were drawn in normal brain tissue. Radiation dose for all volumes were available. Significant CBV and CBF decrease after radiotherapy was visible in grey matter volumes and showed tendency to recover. High radiation dose regions should be avoided when normalising DSC-MRI derived tumour perfusion values.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords