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Abstract #2908

Can diaphragm motion function as a surrogate for motion of esophageal tumors during treatment?

Sophie E. Heethuis1, Lucas Goense1,2, Alicia S. Borggreve1,2, Peter S.N. van Rossum1,2, Richard van Hillegersberg2, Jelle P. Ruurda2, Stella Mook1, Gert J. Meijer1, Jan J.W. Lagendijk1, and Astrid L.H.M.W. van Lier1

1Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands, 2Department of Surgery, University Medical Center Utrecht, Utrecht, Netherlands

Esophageal tumors show large motion in cranio-caudal direction, with a Peak-to-Peak (P-t-P) range of 2.7 to 24.5mm. In case the motion of the tumor could be followed during radiotherapy treatment, this would enable treatment margin reduction. It is researched whether the motion of the diaphragm is correlated with the breathing motion and drift we can detect in esophageal tumors since it could function as surrogate for tumor motion during treatment. A high correlation was found between both motion patterns and correction of the tumor motion using the diaphragm drift resulted on average in a reduction in P-t-P motion in all patients.

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