Abstract #2915

Reproducibility of Quantitative DW-MRI and DCE-MRI of the Breast in the Community Setting: Preliminary Results

Anna G. Sorace¹, Jack Virostko¹, Stephanie L. Barnes^2,3, Jeffrey Luci⁴, Debra Patt⁵, Boone Goodgame^1,6, Sarah Avery⁷, and Thomas E. Yankeelov^1,2,3

¹Internal Medicine, University of Texas at Austin, Austin, TX, United States, ²Biomedical Engineering, University of Texas at Austin, Austin, TX, United States, ³Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, United States, ⁴Neuroscience, University of Texas at Austin, Austin, TX, United States, ⁵US Oncology Network, Austin, TX, United States, ⁶Seton Medical Center, Austin, TX, United States, ⁷Austin Radiological Association, Austin, TX, United States

Implementation of quantitative DCE-MRI and DW-MRI in the community setting has the potential to impact patient care for a large number of breast cancer patients. Quantitative DW-MRI and DCE-MRI was assessed in phantoms and normal subjects across three sites. In normal subject fibroglandular tissue, the average percent difference in ADC across sites for all subjects was 1.8%, while the average percent difference in the inversion recovery scan and B₁- corrected T₁ map were 14% and 7.3%, respectively. Overall, the results from the phantom and normal subject scans reveal that quantitative MRI can be successfully implemented in the community setting.

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