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Abstract #3102

Cine T1 Mapping: Look-Locker inversion recovery for phase resolved T1-Mapping with B1+ Correction At 3T

Sebastian Weingärtner1,2,3, Chetan Shenoy4, Lothar R. Schad3, and Mehmet Akçakaya1,2

1Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 3Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany, 4Department of Cardiology, University of Minnesota, Minneapolis, MN, United States

Conventionally, evaluation of myocardial T1-times is limited to a single snapshot of the cardiac cycle, leaving much of the dependence between functional and tissue characterization unstudied. Here, we propose an ECG-triggered steady-state Look-Locker technique that allows for functional, cardiac phase-resolved native T1-mapping. Integratedly acquired phase-resolved B1+-maps are used for T1-time correction. High accuracy and good consistency of the T1-times across cardiac phases is shown in phantom scans. In-vivo T1-times show slight underestimation and similar precision compared to saturation-recovery T1-mapping. High visual image quality at all cardiac phases is obtained at temporal resolutions up to 40ms in a single breath-hold.

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