Meeting Banner
Abstract #3120

Whole-brain vessel wall imaging within 5 minutes using compressed sensing accelerated IR-SPACE

Zhaoyang Fan1, Xiaoming Bi2, Marcel Maya3, Qi Yang1,4, Shlee Song5, Nestor Gonzalez6, Schlick Konrad5, Esther Raithel7, Christoph Forman7, Gerhard Laub2, and Debiao Li1

1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Siemens Healthcare, Los Angeles, CA, United States, 3Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 4Xuanwu Hospital, Beijing, People's Republic of China, 5Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 6Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 7Siemens Healthcare, Erlangen, Germany

Inversion-recovery (IR) prepared SPACE was recently proposed as a whole-brain intracranial vessel wall imaging technique. This work aimed to investigate the feasibility of accelerating the scan from 8 min to <5 min using compressed sensing (CS). A prototype CS IR-SPACE sequence was implemented on a 3T system. Wavelet sparse regularization (λ) and iteration (Iter) were optimized for the scenario of sampling 15% of k-space data based on a volunteer study. Image quality was visually comparable between CS IR-SPACE and regular IR-SPACE scans. In addition, CS IR-SPACE and IR-SPACE showed comparable lesion delineation quality in patients despite markedly different scan times.

This abstract and the presentation materials are available to members only; a login is required.

Join Here