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Abstract #3126

Evaluation of Four Injection Strategies for High Spatial Resolution Gadobenate Dimeglumine-Enhanced MR Angiography

Gregory J Wilson1 and Jeffrey H Maki1

1Radiology, University of Washington, Seattle, WA, United States

Four injection profiles were evaluated in 40 subjects (10 each). The profiles were designed to provide a signal intensity plateau for a 20 second contrast-enhanced MR angiography scan, using gadobenate dimeglumine. The injection profiles were: 1) standard, non-diluted, 1.6 mL/sec; 2) diluted, 1.6 mL/sec; 3) diluted, bi-phasic, and 4) diluted, patient-tailored. All subjects received a total dose of 0.1 mmol/kg, divided between a test bolus and a full bolus. The “diluted” protocols included dilution of the total dose to 40 mL with normal saline. Signal intensity profiles were measured and analyzed for width of plateau (FW80M) and peak signal intensity.

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