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Abstract #3132

Simultaneous Bright and Black Blood Whole Heart Phase Sensitive Inversion Recovery (PSIR) for Non Contrast Enhanced Coronary Lumen and Plaque Characterization

Giulia Ginami1, Radhouene Neji2, Rene Botnar1, and Claudia Prieto1

1Division of Imaging Sciences and Biomedical Engineering, King’s College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

This study introduces a 3D whole-heart sequence with image-based navigation for non-contrast enhanced coronary lumen and coronary thrombus/haemorrhage characterization. The sequence is based on a phase sensitive inversion recovery (PSIR)-like approach enabling the acquisition of two bright-blood datasets for visualization of the coronary lumen and estimation of motion parameters. Furthermore, a third, fully co-registered dark-blood dataset for thrombus/haemorrhage characterization is obtained from the PSIR reconstruction. With the proposed approach the coronary lumen is visualized with improved SNR/CNR and vessel sharpness when compared to a conventional T2 prepared coronary MRA acquisition. In addition, effective blood signal suppression and feasibility for thrombus visualization is shown with the PSIR reconstructed black-blood dataset.

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