Meeting Banner
Abstract #3143

Accelerated Cardiac Cine “Watermark” MRI provides Cardiac Function via Magnitude Cine and 2D Myocardial Strain via Spatially Modulated Phase

Ronald J Beyers1, Davis M Vigneault2,3,4, Nouha Salibi1,5, David A Bluemke4, and Thomas S Denney1

1MRI Research Center, Auburn University, Auburn, AL, United States, 2Department of Engineering Science, University of Oxford, Oxford, United Kingdom, 3Sackler School of Graduate Biomedical Sciences, School of Medicine, Boston, MA, United States, 4Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, United States, 5MR R&D, Siemens Healthcare, Malvern, PA

We developed a parallel imaging accelerated Cine Watermark (CWM) sequence to provide normal cine magnitude images plus phase image-only multi-directional spatial encoding for quantitative cine strain -- while requiring no extra operator effort. Spatial cosine modulation post-processed by complex image sum/differencing produced separate normal magnitude cine and unique phase-only spatial modulation for strain calculation. In vivo human scans demonstrated good magnitude cine and phase-only quantified displacement. Cardiac strains were tracked by a novel non-linear least squares method combining quadratic b-spline contours, nearest neighbor optimized phase tracking, and physically-motivated regularizers. Cardiac left ventricular, short-axis, circumferential strain results agreed with previous literature.

This abstract and the presentation materials are available to members only; a login is required.

Join Here