Shape analysis of cardiac chambers has important implications for cardiac diseases, most extensively studied in mitral regurgitation (MR). Here we present a novel algorithm for fitting surfaces to the endocardium of all four chambers through the entire cardiac cycle and demonstrate its use in patients with MR. This algorithm, which is based on standard CMR acquisitions, demonstrates improved visualization of the chambers and their function, which can help cardiologists and surgeons in treatment planning in conditions such as mitral regurgitation.
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