Abstract #3209

Variable Density CAIPIRINHA for Highly Accelerated Volumetric Dynamic Contrast-Enhanced Imaging of Liver

Fuyixue Wang^1,2, Zijing Dong¹, Feiyu Chen^3,4, Yuxin Hu^3,4, Jia Ning¹, Feng Huang⁵, and Huijun Chen¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People's Republic of China, ²Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, ³Department of Radiology, Stanford University, Stanford, CA, United States, ⁴Department of Electrical Engineering, Stanford University, Stanford, CA, United States, ⁵Neusoft Medical System, People's Republic of China

Dynamic Contrast-Enhanced (DCE) imaging is widely used in detection and characterization of many liver diseases. In clinical practice, breath holding is commonly used to overcome respiratory motion and get high quality images. However, long breath holds can be painful or unavailable for some patients. To address this problem, we present a variable density 2D CAIPIRINHA sampling technique with a novel reconstruction framework for highly accelerated volumetric DCE liver imaging. Simulation and in-vivo experiments were performed to evaluate the performance of the proposed method compared with other current techniques. The results show great improvement of image quality within shorter acquisition time.

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