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Abstract #3217

Interobserver reproducibility of blood flow measurements with an abdominal 4D flow MRI sequence with spiral sampling and compressed sensing

Octavia Bane1, Steven Peti2, Mathilde Wagner1,3, Stefanie Hectors1, Hadrien A Dyvorne1,4, and Bachir Taouli1,2

1Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 3Radiology, Groupe Hospitalier Pitié Salpêtrière, Paris, France, 44Catalyzer, Guilford, CT, United States

Our study evaluated the interobserver reproducibility of flow quantification in abdominal vessels using a novel 4D flow phase-contrast (PC) MRI sequence. The effect of liver fibrosis on blood flow metrics was also examined in 20 patients. Time-averaged vessel cross-section area, through-plane velocity and volume flow measured in 14 abdominal vessels in a subset of 10 patients were found to have acceptable interobserver agreement (Cohen’s kappa 0.762). A significant increase in the hepatic artery velocity and flow, splenic vein area and flow, middle hepatic vein velocity and flow, and right hepatic vein velocity was observed in patients with advanced fibrosis/cirrhosis.

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