Our study evaluated the interobserver reproducibility of flow quantification in abdominal vessels using a novel 4D flow phase-contrast (PC) MRI sequence. The effect of liver fibrosis on blood flow metrics was also examined in 20 patients. Time-averaged vessel cross-section area, through-plane velocity and volume flow measured in 14 abdominal vessels in a subset of 10 patients were found to have acceptable interobserver agreement (Cohen’s kappa 0.762). A significant increase in the hepatic artery velocity and flow, splenic vein area and flow, middle hepatic vein velocity and flow, and right hepatic vein velocity was observed in patients with advanced fibrosis/cirrhosis.
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