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Abstract #3224

Accurate Flow MRI: the importance of velocity distribution asymmetry

Antoine Vallatos1, Haitham F. I. Al-Mubarak1, James M. Mullin1, and William M. Holmes1

1Glasgow Experimental MRI Centre, Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, United Kingdom

This work proposes a theoretical and experimental investigation into the unexplored effect of asymmetric distribution of intra-voxel velocities on the accuracy of Flow MRI. Our experimental results show that asymmetric velocity distributions can compromise the linearity of measured phase against applied gradient, leading to important velocimetry errors. A theoretical expression of the observed phase measurement errors is introduced, relating them to velocity distribution properties such as variance, skewness and kurtosis. This enables to explain previously reported velocimetry errors and propose solutions so as to increase the accuracy of velocity measurements.

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