Meeting Banner
Abstract #3247

Analysis of Coronary Contrast Agent Transport in Bolus Based Quantitative Myocardial Perfusion MRI Measurements with Computational Fluid Dynamics (CFD) Simulations in High Performance Computing (HPC) Environments

Johannes Martens1, Sabine Panzer1, Jeroen van den Wijngaard2, Maria Siebes2, and Laura Maria Schreiber1

1Comprehensive Heart Failure Center, University Hospital Wuerzburg, Wuerzburg, Germany, 2Dept. of Biomedical Engineering & Physics, Academic Medical Center, Amsterdam, Netherlands

Aim of the project is the execution of computationally extremely challenging CFD simulations of blood flow and contrast agent (CA) transport in coronary arteries on HPC clusters. Therefore scalability testing is performed to assess the suitability of applied software codes in HPC environments. Cardiovascular 3D-models are extracted from high-resolution cryomicrotome imaging data and meshed with computational grids. Navier-Stokes-equations for blood flow and the advection-diffusion-equation for CA transport are solved to obtain CA bolus dispersion in the epicardial vessels. We find indications of asymptotically decreasing dispersion effects with increasing vessel generation.

This abstract and the presentation materials are available to members only; a login is required.

Join Here