Abstract #3268

Interleaved 31P-MR spectroscopy and cine 1H-MR imaging of the human heart at 3 Tesla

Madeleine Daemen^1,2, Aart J. Nederveen¹, Jeroen A.L. Jeneson^1,3, Gustav J. Strijkers⁴, and Adrianus J. Bakermans¹

¹Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, ²Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, ³Neuroimaging Center, University Medical Center Groningen, Groningen, Netherlands, ⁴Department of Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, Netherlands

Changes in the myocardial energy homeostasis have been linked to decreases in cardiac pumping performance. Current MR practice requires two consecutive recordings of ³¹P-MRS and ¹H-MRI to assess both aspects of heart physiology, with consequently long scan times, considerable patient burden, and potentially a mismatch between data from separate sessions. By efficiently interleaving 3D ISIS acquisitions for localized ³¹P-MRS with short-axis cine ¹H-MR imaging, both myocardial energy status as well as left-ventricular ejection fraction could be quantified from MR data that were acquired essentially simultaneously.

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