Kidney cancer is the third most common genitourinary malignancy in the US and leads to over 14,000 deaths and over 61,000 new cancer diagnoses per year. Since metabolic pathways affect the development of several malignancies, MRS was applied to highlight the existing alteration between adjacent benign and cancer tissues. Furthermore, comparison of fresh-frozen paired samples was performed to assess whether such strategy may interfere and deliver different results. This approach was able to discriminate according to pathological condition (benign-tumor) and showed no significant differences in fresh-frozen pairs.
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