Meeting Banner
Abstract #3304

Metabolomic Analysis by HRMAS-MRS: Preliminary Study for Tumor Diagnosis

Francesco L Palmas1,2, Sarah L Prophet3, Lindsey L Vandergrift3, Taylor L. Fuss3, Shulin Wu3, Chin-Lee Wu3, Adam Feldman3, and Leo L. Cheng3

1Pathology, Massachusetts General Hospital, Charlestown, MA, United States, 2Chemical and Geological Sciences, University of Cagliari, Cagliari, Italy, 3Massachusetts General Hospital, Charlestown, MA, United States

Kidney cancer is the third most common genitourinary malignancy in the US and leads to over 14,000 deaths and over 61,000 new cancer diagnoses per year. Since metabolic pathways affect the development of several malignancies, MRS was applied to highlight the existing alteration between adjacent benign and cancer tissues. Furthermore, comparison of fresh-frozen paired samples was performed to assess whether such strategy may interfere and deliver different results. This approach was able to discriminate according to pathological condition (benign-tumor) and showed no significant differences in fresh-frozen pairs.

This abstract and the presentation materials are available to members only; a login is required.

Join Here