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Abstract #3313

Mapping Vascular Behaviour in Lung Perfusion of two-year old children after Congenital Diaphragmatic Hernia Repair using  Tissue Similarity Maps

Dimitrios Markellos1, Meike Weis2, Thomas Schaible3, Stefan O Schoenberg2, Lothar R Schad1, and Frank G Zöllner1

1Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany, 2Department of Radiology and Nuclear Medicine, Heidelberg University, Mannheim, Germany, 3Department of Neonatology, University Medical Center Mannheim, Mannheim, Germany

Congenital Diaphragmatic Hernia (CDH) is associated with lung hypoplasia reflected in decreased pulmonary microcirculation and secondary pulmonary hypertension. Using tissue similarity maps (TSM), Haacke et al. demonstrated mapping vascular behaviour and calculating relative pulmonary blood volume (rPBV) maps in perfusion weighted imaging of the brain. In this study we have investigated the significance of the TSM technqiue for lung perfusion imaging in two-year old children after CDH repair.

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