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Abstract #3318

Steady-state Free Precession for Improved Signal to Noise in Lung Ventilation Imaging with 19F Perfluoropropane at 1.5 T

Adam Maunder1, Neil J Stewart1, Madhwesha Rao1, Fraser J. L. Robb1,2, and Jim M Wild1

1Unit of Academic Radiology, University of Sheffield, Sheffield, United Kingdom, 2GE Healthcare Inc., Aurora, OH, United States

Fluorinated gas MRI is a promising method for pulmonary ventilation imaging that does not require additional polarization equipment. To date, short echo time spoiled gradient echo sequences with long repetition times relative to T1 have been employed for lung ventilation imaging in humans. Here, we present an optimization of steady state free precession sequences for imaging of C3F8 gas in lungs, and demonstrate that image signal-to-noise ratio may be improved by exploiting the short T1, and relatively long T2.

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