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Abstract #3335

The Effects of 2D Navigator Distortion and Noise Level on Interleaved EPI DWI Reconstruction: A Simulation Study

Erpeng Dai1, Xiaodong Ma1, Zhe Zhang1, Chun Yuan1,2, and Hua Guo1

1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People's Republic of China, 2Vascular Imaging Laboratory, Department of Radiology, University of Washington, Seattle, WA, United States

Interleaved EPI (iEPI) with a 2D navigator is an effective way to acquire high-resolution and less-distorted DWI. The inter-shot phase variations can be corrected with acquired 2D navigator. However, the performance is limited by the geometric distortion mismatch between the navigator-echo and image-echo. Parallel imaging can be used to reduce the navigator distortion, but can cause noise amplification. Previously, the effects of the navigator were studied with in vivo experiments, but the effects of distortion and noise were mixed together. In this study, the effects of navigator distortion and noise are studied individually with both DWI and DTI simulations.

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