Stretched-exponential diffusion weighted imaging (SEM-DWI) provided a more accurate estimate than conventional DWI in grading gliomas. Moreover, SEM-DWI derived α value could effectively differentiate EGFR negative and positive group and had a significantly negative correlation with EGFR expression . Therefore, it was concluded that SEM-DWI might be applied as an effective imaging biomarker in grading gliomas and predicting of EGFR status and thus in guiding individual treatment and targeted therapy.
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