Meeting Banner
Abstract #3501

Differentiating Contributions To Diffusional Kurtosis in the Brain with Symmetrized Double-PFG MRI

Jeffrey Paulsen1, Iris Yuwen Zhou2, and Phillip Zhe Sun2,3

1Independent, Boston, MA, United States, 2Athinoula A. Martios Center for Biomedical Imaging, MGH and Harvard Medical School, Charlestown, MA, United States, 3Department of Radiology, University of Illinois at Chicago

Kurtosis imaging enables valuable diagnostics of stroke and other tissue pathologies. It can arise directly from restricted diffusion, but also from sub-voxel heterogeneity in the ADC. Utilizing double diffusion contrast, we are able to remove these heterogeneity contributions. We show this targeted ‘microscopic’ kurtosis contrast yields unique contrast in-vivo in a live rat brain: highlighting white/gray matter boundaries.

This abstract and the presentation materials are available to members only; a login is required.

Join Here