Abstract #3524

Diffusion Kurtosis Imaging with the breath hold method for staging of hepatic fibrosis: Potential as additional sequence in a clinical routine

Daisuke Yoshimaru^1,2, Toshiaki Miyati², Yuichi Suzuki³, Yuhki Hamada¹, Nozomi Mogi⁴, Ayumu Funaki¹, Ayumi Tabata¹, Maki Tobari⁵, and Takayoshi Nishino⁵

¹Department of Medical Technology Image Laboratory, Tokyo Women’s Medical University Yachiyo Medical Center, Yachiyo, Japan, ²Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, kanazawa, Ishikawa, Japan, ³Department of Radiological Service, The University of Tokyo Hospital, Japan, ⁴Department of Radiological Service, Tokyo Women's Medical University Medical Center East, Japan, ⁵Department of gastroenterological medicine, Tokyo Women’s Medical University Yachiyo Medical Center, yachiyo, Japan

We evaluated hepatocellular degeneration using DKI analysis with the breath hold technique compared with the pathological appearance about chronic hepatic diseases and hepatic fibrosis. Using this DKI method in the liver the stage of hepatic fibrosis can be classified into normal hepatic fibrosis and early hepatic fibrosis, and into early hepatic fibrosis and advanced hepatic fibrosis. Thus, we consider that DKI analysis can reflect pathological classification accurately. We considere that this DKI method will be required to evaluate the degree of hepatic fibrosis and to monitor the progress of hepatic fibrosis as an additional sequence in a clinical routine.

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