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Abstract #3543

Comparing liver fat quantification obtained with Complex Chemical Shift-Encoded MRI and Conventional method in an oncologic population sample.

Alessandra Borgheresi1, Davinia Ryan1, Simone Krebs1, Sarah Eskreis-Winkler1, and Lorenzo Mannelli1

1Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States

Chemotherapy is hepatotoxic. Since steatosis is an early sign of hepatotoxicity, an accurate estimation of the changing of fat liver concentration would be useful in the management of oncologic patients. The purpose of this study was to compare fat liver concentration estimated by T1-weightened-in-and-out-of-phase (IOP) imaging with the one obtained by IDEAL-IQ method in an oncologic patients population with unknown liver iron concentration. A statistical difference was demonstrated between fat fraction estimated with conventional IOP imaging and IDEAL-IQ method.

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